This week our resident health experts Elliot Overton and Doug DiPasquale interview Dr. Chandler Marrs on the essential roles of vitamin B1 (thiamine), mitochondrial bioenergetics, and how to stay healthy in our toxic modern world.
Dr. Chandler Marrs is a researcher and writet who holds a PhD in experimental psychology/neuroendocrinology, where the research focus was on female hormones and women’s health. She co-authored the book “Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition”, and is also the founder of the health website and online journal “Hormones Matter”.
In her time as a writer she has written well over 200 articles, and her research has gradually moved over to medication-adverse events, the mitochondria, and examining the roles of nutrition in mitochondrial function.
When she is not busy at work, Dr Marrs is involved in competitive powerlifting and is also a self-proclaimed long-time jock!
Here’s where you can find Dr. Marrs:
Her website:
Old Ladies Lift:
YT Channel:
Time stamps:
1:59 What led you to study experimental psychology and the other things you’ve achieved since then?
6:20 What is thiamine and why it is important
12:20 You said it is in whole foods – what part of the grain is it in?
14:20 What happens when you are low in thiamine? How does this manifest in the body?
19:39 Are there any cases that stood out with regards to thiamine improving their health?
23:37 Mega-dosing thiamine
26:12 Can you briefly explain the different types of thiamine?
29:21 Is TTFD (thiamine tetrahydrofurfuryl disulfide) better than IV thiamine?
34:00 When metformin is present thiamine can’t get in, not as safe as presented
37:45 What do you think of the many chemicals we come into contact with?
40:07 What kind of diet is beneficial in maintaining or providing the body with thiamine?
43:55 Some foods inhibit thiamine absorption. How significant do you think that is?
45:25 If someone is severely thiamine deficient, how long does it take to build up their stores?
47:11 How prevalent is thiamine deficiency in the general population?
52:20 What else besides thiamine is wrong?
59:33 What are your thoughts on supplementing with thiamine for someone on long-term medication?
1:01:09 Upcoming plans
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The information presented on this show is not intended to replace a qualified health care professional and is not intended as medical advice.
The intent is to share knowledge and information we encounter during our research and encourage you to do the same!

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28 thoughts on “Dr. Chandler Marrs on Vitamin B1 (Thiamine) – Mitochondria's Gateway to Energy

  1. Sooo thankful I found Elliott 🙏. Thank you for realizing the importance of getting this info out into the world 🙏🙏🙏. I’ve learned sooo much 💕. I hope to get a consult with you soon.

  2. Did she really try and blame the Trump administration for our current food crisis? Obama appointed Monsanto VP to head our FDA! Why do people ignore this? Globalists are the problem.

  3. Thanks for all the great info! I was just diagnosed for having low B1 and neurotransmitters. I’m definitely amping up the Whole Foods.👍

  4. This was an educationally excellent and fun interview, really good questions, good flow. Such research and popularizing talks and shows like this are communicating a life-saving understanding which very smart people in medical schools have no exposure to, unfortunately, so that we — laymen with no medical training — have to look after our health and the health of those around us, educate ourselves however we can, without the benefit of medical training, labs, etc. God bless your research and increase exposure to save more people from the age of arrogant ignorance, greed, ego, etc.

  5. If a test for the active form of B1? Also when on digestive healing diet , SCD ( ) , read that some "bad bugs" can use up our thiamine so we need way more. The other reasons for thiamine defic., was it said from transporter problems and toxins (any cures?)? Have been getting tired again, will check in mineral, such as iron defic. or ? Or maybe its the added fluoride to our drinking water. Is there a mitochondria test?

  6. I love the title of the book you're working on, "Not Quite Fatal," because that's how conventional medicine sees it–unless it kills you quickly, it's okay.

  7. Water soluble? Fat soluble? What’s the mechanism referred to? Please teach us more, don’t avoid the details. Almost sounded like Dr. Marrs was’t sure which was which for a moment. Will the real Dr Marrs please stand up?
    Still, very appreciative of this content. Immediately bought the books. Alinamin purchase was in transit even before watching this talk. Genova NutriEval and GI Effects labs offer helpful guidance.

  8. I’d love to read the book, but it’s just a tad too expensive. Anyway, I’ve struggled with my breathing for over 15 years, always blaming it on my B12 deficiency, but even when I had decent energy, I still noticed “labored breathing”….air hunger, chronic hyperventilation, etc. I finally figured out the B1 component of my issues. I’ve been working my way up, and for the first time in years, my breathing feels “freer”. I’m up to 700 mg, and I was afraid of going higher, but if someone is taking 2 grams, then I guess it’s worth a try to keep (gradually) increasing. How often should one increase the dose, and by how much? How do you know when you shouldn’t go any higher? Will there be a side-effect of over-supplementation? Is it beneficial to include various types of B1? At high doses, does one risk getting out of balance with the other Bs? Thanks.

  9. "Sepsis Cure" Thiamine & Vitamin C….. Do you make a comparison to BeriBeri or other historical context… and how in the "modern era" thiamine deficiency doesn't exist / justina thing of the past… and that Thiamine deficiency is Sepsis … that maybe in our diet mix is Sepsis but what else went with beriberi or is it just the rest of our medicine that keeps em alive when they would have dropped… or is Sepsis just a chronic moderate deficiency? Or a partial thiamine function suppression due to various environmental or dietary toxins = fluoride/ chlorine / etc in water…glyphosate…etc… after coming across your videos and watching this a couple times this came back to my memory https://www.npr.org/sections/health-shots/2018/05/11/609149556/can-a-cocktail-of-vitamins-and-steroids-cure-a-major-killer-in-hospitals …funny thing is when I first read about the sepsis b1 and c = I never really thought about it in any way except for those with sepsis… as opposed to those with a mitochondrial issue…

  10. Dr. Doug asked for his MD friend in the EU: could they use intramuscular thiamin in an IV (as that's what was available to them) … @ChandlerMarrs didn't quite answer. I'd like to know, too.

  11. I really didn't get as much out of this conversation the interviewer was great but the expert didn't talk a lot about co-factors.

  12. Great interview. Thanks! There is transdermal thiamine patches. Companies sell them as mosquito patches so this would be great for most children as long as they don't have sensory issues.

  13. Great discussion…but I seriously doubt we have more stress "placed" on us compared to 100-200, 700 or even 10,000 years ago.

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